NiCHe Case Study – Adipic Acid Derivative
- 3rd July 2015
- Posted by: admin
- Category: CaSe Studies
An EU based Pharmaceutical Company needed to source an Adipic Acid Derivative as a starting material for a new process to an existing end product.
- Customer first contacted NiCHe Materials Ltd in November 2011 to source a custom material. The Chemical was available commercially but not in the purity required by the customer.
- Target purity was Assay > 99%, critical parameter free Adipic Acid content target < 0.05%
- Manufacturer developed GC Test Method to measure and quantify free Adipic Acid
- Manufacturer produced target quality (Assay 99.1%) and met the free Adipic Acid content (0.04%). Also qualified and quantified the remaining impurity, Diethyl Adipate 0.75%, retention time 10.1 minutes.
NiCHe Materials Ltd met the 1kg R&D requirements for this project.
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